Chinese Journal of Tissue Engineering Research ›› 2015, Vol. 19 ›› Issue (26): 4258-4264.doi: 10.3969/j.issn.2095-4344.2015.26.030

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Open fracture repair: wound infection, implant selection and evaluation of prognosis

Ma Xiang-yu, Wang Dong   

  1. the Second Hospital of Shanxi Medical University, Taiyuan 030000, Shanxi Province, China
  • Received:2015-03-30 Online:2015-06-25 Published:2015-06-25
  • Contact: Wang Dong, M.D., Chief physician, Doctoral supervisor, the Second Hospital of Shanxi Medical University, Taiyuan 030000, Shanxi Province, China
  • About author:Ma Xiang-yu, Studying for master’s degree, the Second Hospital of Shanxi Medical University, Taiyuan 030000, Shanxi Province, China

Abstract:

BACKGROUND: Open fractures often present soft-tissue defects, high-risk infection, and fracture with bone defect, often lead to more postoperative complication, defect of limb function, and bring great difficulties to clinical treatment. There is some controversy in the treatment of such fracture. Relevant animal experiment and clinical study become the hotspot in recent years.
OBJECTIVE: To review some controversy about open fracture treatment and latest research.
METHODS: A computer-based online search of China National Knowledge Infrastructure database and PubMed was performed for articles published from January 2005 to January 2015. Key words included “Open fracture, Evaluation and prognosis of injury, Antibiotics, Debirdement, Treatment of fracture, Wound repair”. More than 100 literatures were retrieved, and 47 articles met the inclusion criteria.
RESULTS AND CONCLUSION: After a large number of animal experiments and clinical application, open fracture debridement, prevention of infection, implant selection and evaluation of prognosis had been deeply studied, especially the study of implant treatment of bone defects. Metal three-dimensional printer has changed the traditional concept of implant. Nano titanium dioxide /PEEK bioactive composite materials have become a hot research in recent years.

中国组织工程研究杂志出版内容重点:人工关节;骨植入物;脊柱骨折;内固定;数字化骨科;组织工程

Key words: Fractures, Open, Prostheses and Implants, Debridement

CLC Number: